My tip is Very Slow on legend. Then tweak from there.I've been enjoying the game playing as career / pro. My biggest issue is the cut scenes or a behind etc resetting the position of your career player. Very frustrating.
Also if you start as a Rookie the game takes you through the TAC then VFL system rather than through the draft.
Other than that the gameplay is enjoyable. I find 7.5 minutes gives the most realism in terms of possessions etc and whomever suggested playing it in slow deserve a medal.
On iPhone using BigFooty.com mobile app
I'll take screenshots of my sliders tonight- if anyone wants to/does try them, let me know what you think! (Also remember I manually tweaked key players stats, slowed down almost all ruckman, increased kicking distance of people like franklin and reduced for players like Garlett and stevie J). Also play with wind indicators off to make set shots more random (have kick charge meter pretty high but kick distance turned up meaning nail a meter at the top and you can dob it from 55-60)