I wouldn't do anything different, moving Newcombe off the ball makes us weaker. Much rather have an Essendon player in their midfield that doesn't want the ball as they'll be playing a man down. I can't see Setterfield bothering Newcombe much at all to be honest.I hope the Duke rests forward if Setterfield is applying a hard tag, he can take the ball-ups and then push forward. He'll have Setterfield beat in the air and could throw off their plan.
Though if there's no Worpel and no Day then we'd be running an inexperienced midfield. Time for Nash, Ward, Mackenzie and hopefully Hustwaite to shine.