Although you cant prepare for it, no doubt there will be more Covid cases during the year as that seems to be on the increase so players will go in and out of the side for a week. The mental health issue seems to be increasing as well and all of this stuff is basically extra to having injuries,- some short term and some long term.
The player who is adaptable and can play in 1 or 2 positions becomes invaluable.
I reckon this will be one of those years where the premier is the good side who has the most luck with injuries/unavailability - Melbourne won't win the flag if covid runs through the club before the prelim