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Good god....well done on both the record for the biggest copy/paste and the biggest load of shit ever posted on bigfootyNot on the official Ministry of Health prescribed medication for covid but used by GP’s and pushed by the Chairman of the Tokyo Medical Association even up until August. How widespread use on a local level is hard to quantify. This article gives the best breakdown of the situation
「今こそイベルメクチンを使え」東京都医師会の尾崎治夫会長が語ったその効能
【読売新聞】ＰＯＩＮＴ ■イベルメクチンが新型コロナの予防にも治療にも効果があるという論文が相次いで発表されているが、すでに「使用国」とされている日本では使用が進んでいない。 ■感染爆発が進む今こそ使用すべきだが、使おうにもイベルメwww.yomiuri.co.jp
Translated
"Now is the time to use ivermectin," Haruo Ozaki, chairman of the Tokyo Medical Association, talked about its efficacy.
2021/08/19 10:55 AM
Contributions Research and Research
Scrap this article
POINT
■Thesis that Ivermectin is effective in preventing and treating COVID-19 has been published one after another, but it has not been used in Japan, which is already considered to be a "country of use".
■It should be used now that the infection explosion is progressing, but there are issues such as not having ibermectin to use it, and not being subject to the government's side effects damage relief system.
■If the Japanese version of the EUA is developed quickly and the doctors on the field can use it, it can be administered to patients staying at home and recuperating. The government should actively work on promoting use.
Delta strains originating in India are raging during the Tokyo Olympics, and the number of infected people continues to spread. Why doesn't Japan use ivermectin, which has been reported in clinical trials in other countries with few reports of side effects? On August 5, we had an emergency interview with President Ozaki of the Tokyo Medical Association, who has been advocating effective use of ivermectin from an early age.
Interviewer and composition Certified NPO, Chairman of the 21st Century Concept Study Group
Scientific journalist Rensei Baba
The peak of the spread of infection that can not be seen yet
――This explosive spread of infection, which is said to be the fifth wave, seems to be still rising to the right. The number of people waiting at home and recuperating is increasing rapidly. How does the Tokyo Medical Association respond?
"When the number of people who wait at home and recuperate increased rapidly in the third wave of January, this was no good, and the Tokyo Metropolitan Medical Association worked together to build a system with the goal of 24-hour support, and up to 37 out of the 47 District Medical Associations. It became. However, the current situation where more than 1000 home recuperators accumulate every day is beyond the limit. Doctors in the clinic can't handle general medical care, vaccination, medical checkup, house call, etc. The public health center is adjusting the hospitalization now. There is also a hospitalization adjustment center in Tokyo, but it has not been established to establish a system that can quickly accept and treat sudden changes of coronavirus patients."
Many clinical trial results are "effective for prevention and treatment".
――If you read the paper on clinical trials of Ivermectin that have been published around the world so far, there are many examples that are effective for prevention and treatment.
"I understand that there are many thesis that Ivermectin is effective in preventing and treating corona, mainly in Latin America and Asia. I'm forced to deal with patients who develop one after another, but there are no effective treatments. The vaccine won't be in time. When such an imminent situation occurs, there is a paper that Ivermectin is effective against corona, so it is a natural response for a clinician to try using this. That's why many doctor-led clinical trial papers came out because of that."
Ivermectin
Ivermectin
――Normally, pharmaceutical companies do large clinical trials to see the effect, but Ivermectin is a special medicine for tropical diseases such as oncocercaemia (river blindness) and lymphatic filariasis, including the World Health Organization (WHO) and other countries around the world It's a drug approved more than 20 years ago. If it's also effective for COVID-19, it's out of adaptation, but it's unavoidable that we decided to use it during the pandemic.
That's right. The medical field of the pandemic is a battlefield. It's the same as Field Hospital. Patients are brought in and their condition gets worse one after another and they die. At that time, there were almost no side effects, and many papers came out that it would work on corona virus, so I understand the doctor's feelings of clinging to this and administering it well."
"Just the other day, a research group of All India Institute of Medical Sciences/AIIMS, which has decided on guidelines for treating coronavirus infections in India, has been I'm publishing a paper that examines the preventive effect of Kuchin. According to it, about 3900 medical workers (staff and students) weighed 0 per kilogram of Ivermectin. As a result of clinical trials divided into three groups of 3 milligrams administered twice every three days, the group that was administered only once, and the group that did not administered it, the number of people who received Ivermectin twice decreased by 83% in COVID-19 infection. It's. The paper was published by the world's first-class research group, so it's very reliable."
――In Japan, we have admitted that Ivermectin will be used for COVID-19 treatment from the "Guide to COVID-19 Treatment Guide for COVID-19" noted on May 18, 2020. Even in the world, Japan is divided into countries where Ivermectin is used.
"In Japan, Ivermectin has been approved as an indication under the product name "Stromectol" for scabies for skin diseases, etc. for a long time, and the revised guide has provided a notice to approve the treatment of COVID-19 as "out of adaptation". I am. Out of adaptation means that it can be used at the discretion of doctors and patients. By the time the notice was issued, 36 clinical trials were conducted in 27 countries in the world, and it was reported that ivermectin was effective in preventing and treating. That's why the Ministry of Health, Labour and Welfare also admitted it out of the scope. If it doesn't work, if it's out, we won't be not going to notice."
The government is positive about using the Diet, but...
――In the Diet, the government is also responding to the use of yvermectin.
"At the budget committee of the House of Representatives on February 17, Katsuhito Nakajima, a member of the Constitutional Democratic Party, proposed about ivermectin, "We should do our best back up the trial so that we can approve it as an early treatment for coronavirus as possible as the country." I did. Minister of Health, Labour and Welfare Tamura said, "It can still be used for non-adaptive use. There is also a way to use it to take it at a medical institution and wait at home. Prime Minister Suga replied, "I think it's a very important medicine for Japan, so I'll do my best," and showed his active efforts. But in reality, we haven't been able to do it."
――Why can't you do it?
"We also investigated what kind of supply system Merck in the United States, which supplies approved drugs in Japan and beyond that. Probably because Merck is developing a therapeutic drug, Ivermectin is not effective in treating and preventing COVID-19, and intends not to use it other than skin diseases such as scabies. In other words, even if you use it for COVID-19, if Merck doesn't actually come out, it won't lead to domestic Ivermectin supply. Even if the doctor writes a prescription for Ivermectin, the pharmacy doesn't have any drugs. This will virtually not be usable."
"But (Merk) says that Ivermectin doesn't work, so there's no need to limit the supply. If it doesn't work, there's no demand. I believe it will work, so it looks like it's blocking the supply."
The reason why generics don't spread is
――Ivermectin's generic chemicals are also manufactured in large quantities in China, India, etc. If Merck doesn't issue it, there should be a way to import and supply it.
That's right. If the "Special Measures Bill for Designation and Use of Specific Drugs for therapeutic Use of New Influenza" (Japanese version EUA* Development Bill) submitted to the House of Representatives led by Mr. Nakajima, who is also a doctor, will be able to use generic preparations. I will do it. But at the moment, the government is not moving at all."
"Another problem is that ivermectin has already been used in many countries in the world, and usage, dosage, safety and effectiveness have been confirmed, but that has not yet been done in the clinical trial stage in Japan. Therefore, Ivermectin is not subject to the damage relief system for pharmaceutical side effects. This makes it difficult for doctors to use. However, even in such anxiety and disadvantageous circumstances, some doctors who are convinced of the effect of ivermectin have prescribed ivermectin at their own risk. I hope the Japanese EUA Development Act will be enacted soon."
*EUA (Emergency Use Authorization) The U.S. Food and Drug Administration (FDA) system that allows the use of unauthorized drugs in case of emergency and expands the application of approved drugs. The merit of using , which is a life-threatening disease that can be recognized as a certain efficacy in the treatment of the disease, exceeds the potential risk of the product and other suitable alternatives to diagnose, prevent or treat diseases. If it is judged that it meets the condition of "い――", it can be used.
――Since it has been admitted that it is not adapted, Japan is divided into "the country of use of Ivermectin" in the world, but it is a system that can not be used in reality.
That's right. In short, the government has not built a system that can supply Ivermectin, so it is not a promotion system. If the Japanese version of the EUA is developed quickly and the doctors in the field can use it, as Minister of Health, Labour and Welfare Tamura responded in the Diet, it can be realistically administered to patients staying at home and recuperating, but the current system can virtually do anything. It is often said that it is "for the safety of the people", but if you don't lose your cautious attitude even in such an emergency, you can only understand that you are sacrificing the safety of the people."
Academic sites and researchers who don't touch themselves
――Is there any other problem in Japan?
"Ivermectin is a drug discovered by Dr. Satoshi Omura and won the Nobel Prize. Whether it really works on Corona or not, Japan should have the ability to work on it ahead of the world. The WHO and the National Institutes of Health (NIH) in the United States continue to take the view that the effect on corona virus is undecided, but since Ivermectin is used all over the world during the pandemic, scientific evidence (evidence) If the clinical trials obtained are conducted by the government and show objective and convincing conclusions, it will lead to an increase in Japanese research standards."
"A group of American clinicians (FLCCC) published the results that ivermectin is effective against corona in South America and Asia, and doctor groups such as Ivermectin Recommendation Organization (BIRD) in the UK have published many papers. We are convinced that it is "effective" from the meta analysis that comprehensively analyzes, and we recommend ivermectin to medical fields around the world. I also told the Japanese Olympic Committee that Ivermectin should be used effectively when holding the Tokyo Olympics, but the government didn't respond to anything."
"There are also problems with academic researchers and university teachers. Many people don't do anything by themselves, and they have their own view that "Ivermectin is undecided whether it will work for coronavirus" issued by international organizations such as WHO and large health organizations in Europe and the United States. Don't do it proactively, it's only moving with people's opinions. Why don't you feel like checking on your own whether Ivermectin works or not? It's sad that there are critics, researchers, and scholars who are always criticizing without doing it. I want Japanese academia to contribute more actively."
The Tokyo Medical Association "I want to work on using it."
――In Japan, clinical trials centered on Kowa, a major pharmaceutical company, are finally scheduled to be conducted. How do you deal with it?
In January 2021, after the exchange of opinions for the development of the vaccination system, Gover nor Yuriko Koike and Chairman Ozaki of Tokyo (left) responded to interviews by the press.
In January 2021, after the exchange of opinions for the development of the vaccination system, Governor Yuriko Koike and Chairman Ozaki of Tokyo (left) responded to interviews by the press.
"The Tokyo Metropolitan Government and the Medical Association are planning to actively support and cooperate with this clinical trial. I decided to actively search and provide medical institutions to cooperate with. There's nothing we can do in a country that relies on vaccines and therapeutic drugs developed by foreign countries. It is our thing to properly put out the data of Ivermectin ourselves and aim to contribute to the severity and decrease in death as a Japanese."
――What should the Japanese health system learn from the experience of the coronavirus pandemic?
"Unduring the Japan's universal insurance system, it has been clear that the response in the event of a pandemic like this time is severe. Private medical facilities are managed by increasing the occupancy rate to the fullest and increasing efficiency. Under such situations, it is extremely difficult to be told to deal with it because the number of infected people has increased rapidly like this time.
"For example of countermeasures, we build hospitals with about 1,000 vacant beds at public medical institutions and hospitals, and usually operate them as training and training institutions for research facilities, doctors, nurses, and laboratory technicians, and in the event of a pandemic, doctors There is a way to use it as a medical institution. We will hone our skills, train human resources, and make it a system that allows us to introduce human resources that we have nurtured in the event of a pandemic. I think there are also challenges to materialize the operation method, but I think we should consider and study in the future."
after the interview
There is also a backlash against WHO who is cautious about use.
Under the circumstances where Delta strains (Indian mutants) are about to replace almost all of the infected people in Japan, the number of new cases of COVID-19 is hitting a record high every day.
The number of home recuperators in Tokyo exceeds 20,000 and more than 70,000 nationwide. Katsuhito Nakajima, a member of the House of Representatives, who is also a doctor, said, "Antibody cocktail therapy is effective, but there are challenges in the amount of security and system development. In order to prevent the severity of coronavirus patients, it is necessary to expand the choice of early treatment." I felt that one of the options was the administration of Ivermectin strongly moving Chairman Ozaki.
Tedros WHO Executive Director
Tedros WHO Executive Director
The evaluation of ivermectin for corona treatment and prevention has not hardened yet. Major health organizations in the world, such as WHO and NIH, maintain the view that "there are no clinical trial results that show evidence enough to convince scientists around the world". However, it is also true that there are many groups of doctors in the United States and the United Kingdom who oppose that "these claims are unfounded".
While some people are seriously ill and die, doctors are working hard day and night in medical settings around the world. India's medical field during the rapid spread of infection was just a battlefield. In medical fields where there are not enough therapeutic drugs or therapeutic equipment, Ivermectin was administered relying on many papers that it was effective against COVID-19, and many cases have greatly affected.
The Indian Bar Association made a document that violently criticized the WHO's not recommending Ivermectin for the use of treatment, saying that it is equivalent to a murder charge to letting patients die, and send it to Secretary-General Tedros and Chief Scientist, and sends the document to the world. It's publishing it to the world.
The medical groups that have the effect of ivermectin are FLCC in the United States and BIRD in the UK. The FLCCC summarizes the results of 63 clinical trials meta-analysis (as of August 15) conducted by 613 scientists (doctors and researchers) around the world for 26,398, and judged as follows.
▽86% of the preventive effect in 14 preventive tests
▽73% improvement effect in 27 initial symptom treatment tests
▽40% improvement effect in 22 severe treatment tests
▽Degraded mortality rate by 61% in 25 clinical trials
About half of the 31 meta-analyzed cases are considered the global clinical trial standards, and randomized controlled trials (RCTs) that emphasize evidence, and 60% of them have improved here. Chairman Ozaki believes this and shows that there may be clinicians who believe in this and try to use ivelmectin for treatment.
The claim to deny ivermectin is also persistent.
On the other hand, it is true that there are persistent voices of doubts and opposition to using ivermectin for the treatment and prevention of corona. I read three papers that have no ibermectin effect, and two of them were pointed out by researchers that there was a mistake in the method of clinical trials. Isn't there any other paper that doesn't work?
Certainly, there were cases where the papers of the Egyptian doctor group, which was "effective", were pointed out that the data was suspected of fabricated and withdrawn. However, as mentioned above, the fact that Ivermectin is overwhelmingly more effective for COVID-19 is unwavering. Ivermectin has almost no side effects, generics are widespread and the price is cheap. The idea of using it is not reckless. Isn't denying the use possible to destroy the countermeasures against the pandemic?
Expect the Japanese EUA bill to be passed.
The Minister of Health, Labour and Welfare Tamura said in the Diet that it can still be used for non-applicable use. There is also a way to take (Ivermectin) at a medical institution and wait at home," he replied. If this is easy to do, there is no need for the Tokyo Medical Association to insist that "Ivermectin should be used".
Chairman Ozaki said, "In non-adaptive use, even if there is a health injury due to side effects, it will not be subject to the relief system, and first of all, there is nothing to prescribe." Unless generic preparations can be used, Ivermectin will continue to be a "medication that can't be used forever" realistically.
Beyond that wall is the enactment of the "Japanese EUA Development Bill" submitted to the Diet by members of the House of Representatives Katsuhito Nakajima of the Constitutional Democratic Party, who are also doctors. However, it is still a shelf due to the recess of the Diet.
Mr. Nakajima, the first proposer, says, "If this bill is passed, everything will be solved." Ivermectin, a scabies treatment, will be available for corona treatment, paving way for the use of generic preparations, and health hazards such as side effects can be remedyed. I think doctors will actively prescribe this.
The vaccination rate for the Japanese people as a whole has not reached about 50% for the first time and 40% for the second time. The biggest concern of President Ozaki of the Tokyo Medical Association, which has the largest regional population in Japan, is to deal with the tightness of medical facilities that accept severe patients, and the sudden change of home care workers. Chairman Ozaki's words had a sense of crisis that we had no choice but to use Ivermectin urgently.
Ivermectin discovered in Japan has the potential to become a "savior" of the coronavirus pandemic. Looking at the clinical trial reports around the world so far, it's impossible that it doesn't work at all. Many countries, including India, have a track record of urgently administering ivermectin to reduce the spread of infection. In an emergency, there is no reason to hesitate to use it for coronavirus infection. I'm sure the utilization of Ivermectin is by no means a "bet".
Sent from my iPad using Tapatalk
www.the-scientist.com
www.forbes.com
And a longish piece that eviscerates the bullshit above.
No, Ivermectin Did Not Help Japan Bring Down Covid-19 Coronavirus Delta Surge
Another claim is that the Covid-19 coronavirus somehow mutated itself into extinction in Japan.
Not on the official Ministry of Health prescribed medication for covid but used by GP’s and pushed by the Chairman of the Tokyo Medical Association even up until August. How widespread use on a local level is hard to quantify. This article gives the best breakdown of the situation
「今こそイベルメクチンを使え」東京都医師会の尾崎治夫会長が語ったその効能
【読売新聞】ＰＯＩＮＴ ■イベルメクチンが新型コロナの予防にも治療にも効果があるという論文が相次いで発表されているが、すでに「使用国」とされている日本では使用が進んでいない。 ■感染爆発が進む今こそ使用すべきだが、使おうにもイベルメ
Translated
"Now is the time to use ivermectin," Haruo Ozaki, chairman of the Tokyo Medical Association, talked about its efficacy.
2021/08/19 10:55 AM
Contributions Research and Research
Scrap this article
POINT
■Thesis that Ivermectin is effective in preventing and treating COVID-19 has been published one after another, but it has not been used in Japan, which is already considered to be a "country of use".
■It should be used now that the infection explosion is progressing, but there are issues such as not having ibermectin to use it, and not being subject to the government's side effects damage relief system.
■If the Japanese version of the EUA is developed quickly and the doctors on the field can use it, it can be administered to patients staying at home and recuperating. The government should actively work on promoting use.
Delta strains originating in India are raging during the Tokyo Olympics, and the number of infected people continues to spread. Why doesn't Japan use ivermectin, which has been reported in clinical trials in other countries with few reports of side effects? On August 5, we had an emergency interview with President Ozaki of the Tokyo Medical Association, who has been advocating effective use of ivermectin from an early age.
Interviewer and composition Certified NPO, Chairman of the 21st Century Concept Study Group
Scientific journalist Rensei Baba
The peak of the spread of infection that can not be seen yet
――This explosive spread of infection, which is said to be the fifth wave, seems to be still rising to the right. The number of people waiting at home and recuperating is increasing rapidly. How does the Tokyo Medical Association respond?
"When the number of people who wait at home and recuperate increased rapidly in the third wave of January, this was no good, and the Tokyo Metropolitan Medical Association worked together to build a system with the goal of 24-hour support, and up to 37 out of the 47 District Medical Associations. It became. However, the current situation where more than 1000 home recuperators accumulate every day is beyond the limit. Doctors in the clinic can't handle general medical care, vaccination, medical checkup, house call, etc. The public health center is adjusting the hospitalization now. There is also a hospitalization adjustment center in Tokyo, but it has not been established to establish a system that can quickly accept and treat sudden changes of coronavirus patients."
Many clinical trial results are "effective for prevention and treatment".
――If you read the paper on clinical trials of Ivermectin that have been published around the world so far, there are many examples that are effective for prevention and treatment.
"I understand that there are many thesis that Ivermectin is effective in preventing and treating corona, mainly in Latin America and Asia. I'm forced to deal with patients who develop one after another, but there are no effective treatments. The vaccine won't be in time. When such an imminent situation occurs, there is a paper that Ivermectin is effective against corona, so it is a natural response for a clinician to try using this. That's why many doctor-led clinical trial papers came out because of that."
Ivermectin
Ivermectin
――Normally, pharmaceutical companies do large clinical trials to see the effect, but Ivermectin is a special medicine for tropical diseases such as oncocercaemia (river blindness) and lymphatic filariasis, including the World Health Organization (WHO) and other countries around the world It's a drug approved more than 20 years ago. If it's also effective for COVID-19, it's out of adaptation, but it's unavoidable that we decided to use it during the pandemic.
That's right. The medical field of the pandemic is a battlefield. It's the same as Field Hospital. Patients are brought in and their condition gets worse one after another and they die. At that time, there were almost no side effects, and many papers came out that it would work on corona virus, so I understand the doctor's feelings of clinging to this and administering it well."
"Just the other day, a research group of All India Institute of Medical Sciences/AIIMS, which has decided on guidelines for treating coronavirus infections in India, has been I'm publishing a paper that examines the preventive effect of Kuchin. According to it, about 3900 medical workers (staff and students) weighed 0 per kilogram of Ivermectin. As a result of clinical trials divided into three groups of 3 milligrams administered twice every three days, the group that was administered only once, and the group that did not administered it, the number of people who received Ivermectin twice decreased by 83% in COVID-19 infection. It's. The paper was published by the world's first-class research group, so it's very reliable."
――In Japan, we have admitted that Ivermectin will be used for COVID-19 treatment from the "Guide to COVID-19 Treatment Guide for COVID-19" noted on May 18, 2020. Even in the world, Japan is divided into countries where Ivermectin is used.
"In Japan, Ivermectin has been approved as an indication under the product name "Stromectol" for scabies for skin diseases, etc. for a long time, and the revised guide has provided a notice to approve the treatment of COVID-19 as "out of adaptation". I am. Out of adaptation means that it can be used at the discretion of doctors and patients. By the time the notice was issued, 36 clinical trials were conducted in 27 countries in the world, and it was reported that ivermectin was effective in preventing and treating. That's why the Ministry of Health, Labour and Welfare also admitted it out of the scope. If it doesn't work, if it's out, we won't be not going to notice."
The government is positive about using the Diet, but...
――In the Diet, the government is also responding to the use of yvermectin.
"At the budget committee of the House of Representatives on February 17, Katsuhito Nakajima, a member of the Constitutional Democratic Party, proposed about ivermectin, "We should do our best back up the trial so that we can approve it as an early treatment for coronavirus as possible as the country." I did. Minister of Health, Labour and Welfare Tamura said, "It can still be used for non-adaptive use. There is also a way to use it to take it at a medical institution and wait at home. Prime Minister Suga replied, "I think it's a very important medicine for Japan, so I'll do my best," and showed his active efforts. But in reality, we haven't been able to do it."
――Why can't you do it?
"We also investigated what kind of supply system Merck in the United States, which supplies approved drugs in Japan and beyond that. Probably because Merck is developing a therapeutic drug, Ivermectin is not effective in treating and preventing COVID-19, and intends not to use it other than skin diseases such as scabies. In other words, even if you use it for COVID-19, if Merck doesn't actually come out, it won't lead to domestic Ivermectin supply. Even if the doctor writes a prescription for Ivermectin, the pharmacy doesn't have any drugs. This will virtually not be usable."
"But (Merk) says that Ivermectin doesn't work, so there's no need to limit the supply. If it doesn't work, there's no demand. I believe it will work, so it looks like it's blocking the supply."
The reason why generics don't spread is
――Ivermectin's generic chemicals are also manufactured in large quantities in China, India, etc. If Merck doesn't issue it, there should be a way to import and supply it.
That's right. If the "Special Measures Bill for Designation and Use of Specific Drugs for therapeutic Use of New Influenza" (Japanese version EUA* Development Bill) submitted to the House of Representatives led by Mr. Nakajima, who is also a doctor, will be able to use generic preparations. I will do it. But at the moment, the government is not moving at all."
"Another problem is that ivermectin has already been used in many countries in the world, and usage, dosage, safety and effectiveness have been confirmed, but that has not yet been done in the clinical trial stage in Japan. Therefore, Ivermectin is not subject to the damage relief system for pharmaceutical side effects. This makes it difficult for doctors to use. However, even in such anxiety and disadvantageous circumstances, some doctors who are convinced of the effect of ivermectin have prescribed ivermectin at their own risk. I hope the Japanese EUA Development Act will be enacted soon."
*EUA (Emergency Use Authorization) The U.S. Food and Drug Administration (FDA) system that allows the use of unauthorized drugs in case of emergency and expands the application of approved drugs. The merit of using , which is a life-threatening disease that can be recognized as a certain efficacy in the treatment of the disease, exceeds the potential risk of the product and other suitable alternatives to diagnose, prevent or treat diseases. If it is judged that it meets the condition of "い――", it can be used.
――Since it has been admitted that it is not adapted, Japan is divided into "the country of use of Ivermectin" in the world, but it is a system that can not be used in reality.
That's right. In short, the government has not built a system that can supply Ivermectin, so it is not a promotion system. If the Japanese version of the EUA is developed quickly and the doctors in the field can use it, as Minister of Health, Labour and Welfare Tamura responded in the Diet, it can be realistically administered to patients staying at home and recuperating, but the current system can virtually do anything. It is often said that it is "for the safety of the people", but if you don't lose your cautious attitude even in such an emergency, you can only understand that you are sacrificing the safety of the people."
Academic sites and researchers who don't touch themselves
――Is there any other problem in Japan?
"Ivermectin is a drug discovered by Dr. Satoshi Omura and won the Nobel Prize. Whether it really works on Corona or not, Japan should have the ability to work on it ahead of the world. The WHO and the National Institutes of Health (NIH) in the United States continue to take the view that the effect on corona virus is undecided, but since Ivermectin is used all over the world during the pandemic, scientific evidence (evidence) If the clinical trials obtained are conducted by the government and show objective and convincing conclusions, it will lead to an increase in Japanese research standards."
"A group of American clinicians (FLCCC) published the results that ivermectin is effective against corona in South America and Asia, and doctor groups such as Ivermectin Recommendation Organization (BIRD) in the UK have published many papers. We are convinced that it is "effective" from the meta analysis that comprehensively analyzes, and we recommend ivermectin to medical fields around the world. I also told the Japanese Olympic Committee that Ivermectin should be used effectively when holding the Tokyo Olympics, but the government didn't respond to anything."
"There are also problems with academic researchers and university teachers. Many people don't do anything by themselves, and they have their own view that "Ivermectin is undecided whether it will work for coronavirus" issued by international organizations such as WHO and large health organizations in Europe and the United States. Don't do it proactively, it's only moving with people's opinions. Why don't you feel like checking on your own whether Ivermectin works or not? It's sad that there are critics, researchers, and scholars who are always criticizing without doing it. I want Japanese academia to contribute more actively."
The Tokyo Medical Association "I want to work on using it."
――In Japan, clinical trials centered on Kowa, a major pharmaceutical company, are finally scheduled to be conducted. How do you deal with it?
In January 2021, after the exchange of opinions for the development of the vaccination system, Gover nor Yuriko Koike and Chairman Ozaki of Tokyo (left) responded to interviews by the press.
In January 2021, after the exchange of opinions for the development of the vaccination system, Governor Yuriko Koike and Chairman Ozaki of Tokyo (left) responded to interviews by the press.
"The Tokyo Metropolitan Government and the Medical Association are planning to actively support and cooperate with this clinical trial. I decided to actively search and provide medical institutions to cooperate with. There's nothing we can do in a country that relies on vaccines and therapeutic drugs developed by foreign countries. It is our thing to properly put out the data of Ivermectin ourselves and aim to contribute to the severity and decrease in death as a Japanese."
――What should the Japanese health system learn from the experience of the coronavirus pandemic?
"Unduring the Japan's universal insurance system, it has been clear that the response in the event of a pandemic like this time is severe. Private medical facilities are managed by increasing the occupancy rate to the fullest and increasing efficiency. Under such situations, it is extremely difficult to be told to deal with it because the number of infected people has increased rapidly like this time.
"For example of countermeasures, we build hospitals with about 1,000 vacant beds at public medical institutions and hospitals, and usually operate them as training and training institutions for research facilities, doctors, nurses, and laboratory technicians, and in the event of a pandemic, doctors There is a way to use it as a medical institution. We will hone our skills, train human resources, and make it a system that allows us to introduce human resources that we have nurtured in the event of a pandemic. I think there are also challenges to materialize the operation method, but I think we should consider and study in the future."
after the interview
There is also a backlash against WHO who is cautious about use.
Under the circumstances where Delta strains (Indian mutants) are about to replace almost all of the infected people in Japan, the number of new cases of COVID-19 is hitting a record high every day.
The number of home recuperators in Tokyo exceeds 20,000 and more than 70,000 nationwide. Katsuhito Nakajima, a member of the House of Representatives, who is also a doctor, said, "Antibody cocktail therapy is effective, but there are challenges in the amount of security and system development. In order to prevent the severity of coronavirus patients, it is necessary to expand the choice of early treatment." I felt that one of the options was the administration of Ivermectin strongly moving Chairman Ozaki.
Tedros WHO Executive Director
Tedros WHO Executive Director
The evaluation of ivermectin for corona treatment and prevention has not hardened yet. Major health organizations in the world, such as WHO and NIH, maintain the view that "there are no clinical trial results that show evidence enough to convince scientists around the world". However, it is also true that there are many groups of doctors in the United States and the United Kingdom who oppose that "these claims are unfounded".
While some people are seriously ill and die, doctors are working hard day and night in medical settings around the world. India's medical field during the rapid spread of infection was just a battlefield. In medical fields where there are not enough therapeutic drugs or therapeutic equipment, Ivermectin was administered relying on many papers that it was effective against COVID-19, and many cases have greatly affected.
The Indian Bar Association made a document that violently criticized the WHO's not recommending Ivermectin for the use of treatment, saying that it is equivalent to a murder charge to letting patients die, and send it to Secretary-General Tedros and Chief Scientist, and sends the document to the world. It's publishing it to the world.
The medical groups that have the effect of ivermectin are FLCC in the United States and BIRD in the UK. The FLCCC summarizes the results of 63 clinical trials meta-analysis (as of August 15) conducted by 613 scientists (doctors and researchers) around the world for 26,398, and judged as follows.
▽86% of the preventive effect in 14 preventive tests
▽73% improvement effect in 27 initial symptom treatment tests
▽40% improvement effect in 22 severe treatment tests
▽Degraded mortality rate by 61% in 25 clinical trials
About half of the 31 meta-analyzed cases are considered the global clinical trial standards, and randomized controlled trials (RCTs) that emphasize evidence, and 60% of them have improved here. Chairman Ozaki believes this and shows that there may be clinicians who believe in this and try to use ivelmectin for treatment.
The claim to deny ivermectin is also persistent.
On the other hand, it is true that there are persistent voices of doubts and opposition to using ivermectin for the treatment and prevention of corona. I read three papers that have no ibermectin effect, and two of them were pointed out by researchers that there was a mistake in the method of clinical trials. Isn't there any other paper that doesn't work?
Certainly, there were cases where the papers of the Egyptian doctor group, which was "effective", were pointed out that the data was suspected of fabricated and withdrawn. However, as mentioned above, the fact that Ivermectin is overwhelmingly more effective for COVID-19 is unwavering. Ivermectin has almost no side effects, generics are widespread and the price is cheap. The idea of using it is not reckless. Isn't denying the use possible to destroy the countermeasures against the pandemic?
Expect the Japanese EUA bill to be passed.
The Minister of Health, Labour and Welfare Tamura said in the Diet that it can still be used for non-applicable use. There is also a way to take (Ivermectin) at a medical institution and wait at home," he replied. If this is easy to do, there is no need for the Tokyo Medical Association to insist that "Ivermectin should be used".
Chairman Ozaki said, "In non-adaptive use, even if there is a health injury due to side effects, it will not be subject to the relief system, and first of all, there is nothing to prescribe." Unless generic preparations can be used, Ivermectin will continue to be a "medication that can't be used forever" realistically.
Beyond that wall is the enactment of the "Japanese EUA Development Bill" submitted to the Diet by members of the House of Representatives Katsuhito Nakajima of the Constitutional Democratic Party, who are also doctors. However, it is still a shelf due to the recess of the Diet.
Mr. Nakajima, the first proposer, says, "If this bill is passed, everything will be solved." Ivermectin, a scabies treatment, will be available for corona treatment, paving way for the use of generic preparations, and health hazards such as side effects can be remedyed. I think doctors will actively prescribe this.
The vaccination rate for the Japanese people as a whole has not reached about 50% for the first time and 40% for the second time. The biggest concern of President Ozaki of the Tokyo Medical Association, which has the largest regional population in Japan, is to deal with the tightness of medical facilities that accept severe patients, and the sudden change of home care workers. Chairman Ozaki's words had a sense of crisis that we had no choice but to use Ivermectin urgently.
Ivermectin discovered in Japan has the potential to become a "savior" of the coronavirus pandemic. Looking at the clinical trial reports around the world so far, it's impossible that it doesn't work at all. Many countries, including India, have a track record of urgently administering ivermectin to reduce the spread of infection. In an emergency, there is no reason to hesitate to use it for coronavirus infection. I'm sure the utilization of Ivermectin is by no means a "bet".
Sent from my iPad using Tapatalk
The part where he says there is a accepted dosage
none of it is offensive, just really really stupid.
Not on the official Ministry of Health prescribed medication for covid but used by GP’s and pushed by the Chairman of the Tokyo Medical Association even up until August. How widespread use on a local level is hard to quantify. This article gives the best breakdown of the situation
「今こそイベルメクチンを使え」東京都医師会の尾崎治夫会長が語ったその効能
【読売新聞】ＰＯＩＮＴ ■イベルメクチンが新型コロナの予防にも治療にも効果があるという論文が相次いで発表されているが、すでに「使用国」とされている日本では使用が進んでいない。 ■感染爆発が進む今こそ使用すべきだが、使おうにもイベルメ
Translated
"Now is the time to use ivermectin," Haruo Ozaki, chairman of the Tokyo Medical Association, talked about its efficacy.
2021/08/19 10:55 AM
Contributions Research and Research
Scrap this article
POINT
■Thesis that Ivermectin is effective in preventing and treating COVID-19 has been published one after another, but it has not been used in Japan, which is already considered to be a "country of use".
■It should be used now that the infection explosion is progressing, but there are issues such as not having ibermectin to use it, and not being subject to the government's side effects damage relief system.
■If the Japanese version of the EUA is developed quickly and the doctors on the field can use it, it can be administered to patients staying at home and recuperating. The government should actively work on promoting use.
Delta strains originating in India are raging during the Tokyo Olympics, and the number of infected people continues to spread. Why doesn't Japan use ivermectin, which has been reported in clinical trials in other countries with few reports of side effects? On August 5, we had an emergency interview with President Ozaki of the Tokyo Medical Association, who has been advocating effective use of ivermectin from an early age.
Interviewer and composition Certified NPO, Chairman of the 21st Century Concept Study Group
Scientific journalist Rensei Baba
The peak of the spread of infection that can not be seen yet
――This explosive spread of infection, which is said to be the fifth wave, seems to be still rising to the right. The number of people waiting at home and recuperating is increasing rapidly. How does the Tokyo Medical Association respond?
"When the number of people who wait at home and recuperate increased rapidly in the third wave of January, this was no good, and the Tokyo Metropolitan Medical Association worked together to build a system with the goal of 24-hour support, and up to 37 out of the 47 District Medical Associations. It became. However, the current situation where more than 1000 home recuperators accumulate every day is beyond the limit. Doctors in the clinic can't handle general medical care, vaccination, medical checkup, house call, etc. The public health center is adjusting the hospitalization now. There is also a hospitalization adjustment center in Tokyo, but it has not been established to establish a system that can quickly accept and treat sudden changes of coronavirus patients."
Many clinical trial results are "effective for prevention and treatment".
――If you read the paper on clinical trials of Ivermectin that have been published around the world so far, there are many examples that are effective for prevention and treatment.
"I understand that there are many thesis that Ivermectin is effective in preventing and treating corona, mainly in Latin America and Asia. I'm forced to deal with patients who develop one after another, but there are no effective treatments. The vaccine won't be in time. When such an imminent situation occurs, there is a paper that Ivermectin is effective against corona, so it is a natural response for a clinician to try using this. That's why many doctor-led clinical trial papers came out because of that."
Ivermectin
Ivermectin
――Normally, pharmaceutical companies do large clinical trials to see the effect, but Ivermectin is a special medicine for tropical diseases such as oncocercaemia (river blindness) and lymphatic filariasis, including the World Health Organization (WHO) and other countries around the world It's a drug approved more than 20 years ago. If it's also effective for COVID-19, it's out of adaptation, but it's unavoidable that we decided to use it during the pandemic.
That's right. The medical field of the pandemic is a battlefield. It's the same as Field Hospital. Patients are brought in and their condition gets worse one after another and they die. At that time, there were almost no side effects, and many papers came out that it would work on corona virus, so I understand the doctor's feelings of clinging to this and administering it well."
"Just the other day, a research group of All India Institute of Medical Sciences/AIIMS, which has decided on guidelines for treating coronavirus infections in India, has been I'm publishing a paper that examines the preventive effect of Kuchin. According to it, about 3900 medical workers (staff and students) weighed 0 per kilogram of Ivermectin. As a result of clinical trials divided into three groups of 3 milligrams administered twice every three days, the group that was administered only once, and the group that did not administered it, the number of people who received Ivermectin twice decreased by 83% in COVID-19 infection. It's. The paper was published by the world's first-class research group, so it's very reliable."
――In Japan, we have admitted that Ivermectin will be used for COVID-19 treatment from the "Guide to COVID-19 Treatment Guide for COVID-19" noted on May 18, 2020. Even in the world, Japan is divided into countries where Ivermectin is used.
"In Japan, Ivermectin has been approved as an indication under the product name "Stromectol" for scabies for skin diseases, etc. for a long time, and the revised guide has provided a notice to approve the treatment of COVID-19 as "out of adaptation". I am. Out of adaptation means that it can be used at the discretion of doctors and patients. By the time the notice was issued, 36 clinical trials were conducted in 27 countries in the world, and it was reported that ivermectin was effective in preventing and treating. That's why the Ministry of Health, Labour and Welfare also admitted it out of the scope. If it doesn't work, if it's out, we won't be not going to notice."
The government is positive about using the Diet, but...
――In the Diet, the government is also responding to the use of yvermectin.
"At the budget committee of the House of Representatives on February 17, Katsuhito Nakajima, a member of the Constitutional Democratic Party, proposed about ivermectin, "We should do our best back up the trial so that we can approve it as an early treatment for coronavirus as possible as the country." I did. Minister of Health, Labour and Welfare Tamura said, "It can still be used for non-adaptive use. There is also a way to use it to take it at a medical institution and wait at home. Prime Minister Suga replied, "I think it's a very important medicine for Japan, so I'll do my best," and showed his active efforts. But in reality, we haven't been able to do it."
――Why can't you do it?
"We also investigated what kind of supply system Merck in the United States, which supplies approved drugs in Japan and beyond that. Probably because Merck is developing a therapeutic drug, Ivermectin is not effective in treating and preventing COVID-19, and intends not to use it other than skin diseases such as scabies. In other words, even if you use it for COVID-19, if Merck doesn't actually come out, it won't lead to domestic Ivermectin supply. Even if the doctor writes a prescription for Ivermectin, the pharmacy doesn't have any drugs. This will virtually not be usable."
"But (Merk) says that Ivermectin doesn't work, so there's no need to limit the supply. If it doesn't work, there's no demand. I believe it will work, so it looks like it's blocking the supply."
The reason why generics don't spread is
――Ivermectin's generic chemicals are also manufactured in large quantities in China, India, etc. If Merck doesn't issue it, there should be a way to import and supply it.
That's right. If the "Special Measures Bill for Designation and Use of Specific Drugs for therapeutic Use of New Influenza" (Japanese version EUA* Development Bill) submitted to the House of Representatives led by Mr. Nakajima, who is also a doctor, will be able to use generic preparations. I will do it. But at the moment, the government is not moving at all."
"Another problem is that ivermectin has already been used in many countries in the world, and usage, dosage, safety and effectiveness have been confirmed, but that has not yet been done in the clinical trial stage in Japan. Therefore, Ivermectin is not subject to the damage relief system for pharmaceutical side effects. This makes it difficult for doctors to use. However, even in such anxiety and disadvantageous circumstances, some doctors who are convinced of the effect of ivermectin have prescribed ivermectin at their own risk. I hope the Japanese EUA Development Act will be enacted soon."
*EUA (Emergency Use Authorization) The U.S. Food and Drug Administration (FDA) system that allows the use of unauthorized drugs in case of emergency and expands the application of approved drugs. The merit of using , which is a life-threatening disease that can be recognized as a certain efficacy in the treatment of the disease, exceeds the potential risk of the product and other suitable alternatives to diagnose, prevent or treat diseases. If it is judged that it meets the condition of "い――", it can be used.
――Since it has been admitted that it is not adapted, Japan is divided into "the country of use of Ivermectin" in the world, but it is a system that can not be used in reality.
That's right. In short, the government has not built a system that can supply Ivermectin, so it is not a promotion system. If the Japanese version of the EUA is developed quickly and the doctors in the field can use it, as Minister of Health, Labour and Welfare Tamura responded in the Diet, it can be realistically administered to patients staying at home and recuperating, but the current system can virtually do anything. It is often said that it is "for the safety of the people", but if you don't lose your cautious attitude even in such an emergency, you can only understand that you are sacrificing the safety of the people."
Academic sites and researchers who don't touch themselves
――Is there any other problem in Japan?
"Ivermectin is a drug discovered by Dr. Satoshi Omura and won the Nobel Prize. Whether it really works on Corona or not, Japan should have the ability to work on it ahead of the world. The WHO and the National Institutes of Health (NIH) in the United States continue to take the view that the effect on corona virus is undecided, but since Ivermectin is used all over the world during the pandemic, scientific evidence (evidence) If the clinical trials obtained are conducted by the government and show objective and convincing conclusions, it will lead to an increase in Japanese research standards."
"A group of American clinicians (FLCCC) published the results that ivermectin is effective against corona in South America and Asia, and doctor groups such as Ivermectin Recommendation Organization (BIRD) in the UK have published many papers. We are convinced that it is "effective" from the meta analysis that comprehensively analyzes, and we recommend ivermectin to medical fields around the world. I also told the Japanese Olympic Committee that Ivermectin should be used effectively when holding the Tokyo Olympics, but the government didn't respond to anything."
"There are also problems with academic researchers and university teachers. Many people don't do anything by themselves, and they have their own view that "Ivermectin is undecided whether it will work for coronavirus" issued by international organizations such as WHO and large health organizations in Europe and the United States. Don't do it proactively, it's only moving with people's opinions. Why don't you feel like checking on your own whether Ivermectin works or not? It's sad that there are critics, researchers, and scholars who are always criticizing without doing it. I want Japanese academia to contribute more actively."
The Tokyo Medical Association "I want to work on using it."
――In Japan, clinical trials centered on Kowa, a major pharmaceutical company, are finally scheduled to be conducted. How do you deal with it?
In January 2021, after the exchange of opinions for the development of the vaccination system, Gover nor Yuriko Koike and Chairman Ozaki of Tokyo (left) responded to interviews by the press.
In January 2021, after the exchange of opinions for the development of the vaccination system, Governor Yuriko Koike and Chairman Ozaki of Tokyo (left) responded to interviews by the press.
"The Tokyo Metropolitan Government and the Medical Association are planning to actively support and cooperate with this clinical trial. I decided to actively search and provide medical institutions to cooperate with. There's nothing we can do in a country that relies on vaccines and therapeutic drugs developed by foreign countries. It is our thing to properly put out the data of Ivermectin ourselves and aim to contribute to the severity and decrease in death as a Japanese."
――What should the Japanese health system learn from the experience of the coronavirus pandemic?
"Unduring the Japan's universal insurance system, it has been clear that the response in the event of a pandemic like this time is severe. Private medical facilities are managed by increasing the occupancy rate to the fullest and increasing efficiency. Under such situations, it is extremely difficult to be told to deal with it because the number of infected people has increased rapidly like this time.
"For example of countermeasures, we build hospitals with about 1,000 vacant beds at public medical institutions and hospitals, and usually operate them as training and training institutions for research facilities, doctors, nurses, and laboratory technicians, and in the event of a pandemic, doctors There is a way to use it as a medical institution. We will hone our skills, train human resources, and make it a system that allows us to introduce human resources that we have nurtured in the event of a pandemic. I think there are also challenges to materialize the operation method, but I think we should consider and study in the future."
after the interview
There is also a backlash against WHO who is cautious about use.
Under the circumstances where Delta strains (Indian mutants) are about to replace almost all of the infected people in Japan, the number of new cases of COVID-19 is hitting a record high every day.
The number of home recuperators in Tokyo exceeds 20,000 and more than 70,000 nationwide. Katsuhito Nakajima, a member of the House of Representatives, who is also a doctor, said, "Antibody cocktail therapy is effective, but there are challenges in the amount of security and system development. In order to prevent the severity of coronavirus patients, it is necessary to expand the choice of early treatment." I felt that one of the options was the administration of Ivermectin strongly moving Chairman Ozaki.
Tedros WHO Executive Director
Tedros WHO Executive Director
The evaluation of ivermectin for corona treatment and prevention has not hardened yet. Major health organizations in the world, such as WHO and NIH, maintain the view that "there are no clinical trial results that show evidence enough to convince scientists around the world". However, it is also true that there are many groups of doctors in the United States and the United Kingdom who oppose that "these claims are unfounded".
While some people are seriously ill and die, doctors are working hard day and night in medical settings around the world. India's medical field during the rapid spread of infection was just a battlefield. In medical fields where there are not enough therapeutic drugs or therapeutic equipment, Ivermectin was administered relying on many papers that it was effective against COVID-19, and many cases have greatly affected.
The Indian Bar Association made a document that violently criticized the WHO's not recommending Ivermectin for the use of treatment, saying that it is equivalent to a murder charge to letting patients die, and send it to Secretary-General Tedros and Chief Scientist, and sends the document to the world. It's publishing it to the world.
The medical groups that have the effect of ivermectin are FLCC in the United States and BIRD in the UK. The FLCCC summarizes the results of 63 clinical trials meta-analysis (as of August 15) conducted by 613 scientists (doctors and researchers) around the world for 26,398, and judged as follows.
▽86% of the preventive effect in 14 preventive tests
▽73% improvement effect in 27 initial symptom treatment tests
▽40% improvement effect in 22 severe treatment tests
▽Degraded mortality rate by 61% in 25 clinical trials
About half of the 31 meta-analyzed cases are considered the global clinical trial standards, and randomized controlled trials (RCTs) that emphasize evidence, and 60% of them have improved here. Chairman Ozaki believes this and shows that there may be clinicians who believe in this and try to use ivelmectin for treatment.
The claim to deny ivermectin is also persistent.
On the other hand, it is true that there are persistent voices of doubts and opposition to using ivermectin for the treatment and prevention of corona. I read three papers that have no ibermectin effect, and two of them were pointed out by researchers that there was a mistake in the method of clinical trials. Isn't there any other paper that doesn't work?
Certainly, there were cases where the papers of the Egyptian doctor group, which was "effective", were pointed out that the data was suspected of fabricated and withdrawn. However, as mentioned above, the fact that Ivermectin is overwhelmingly more effective for COVID-19 is unwavering. Ivermectin has almost no side effects, generics are widespread and the price is cheap. The idea of using it is not reckless. Isn't denying the use possible to destroy the countermeasures against the pandemic?
Expect the Japanese EUA bill to be passed.
The Minister of Health, Labour and Welfare Tamura said in the Diet that it can still be used for non-applicable use. There is also a way to take (Ivermectin) at a medical institution and wait at home," he replied. If this is easy to do, there is no need for the Tokyo Medical Association to insist that "Ivermectin should be used".
Chairman Ozaki said, "In non-adaptive use, even if there is a health injury due to side effects, it will not be subject to the relief system, and first of all, there is nothing to prescribe." Unless generic preparations can be used, Ivermectin will continue to be a "medication that can't be used forever" realistically.
Beyond that wall is the enactment of the "Japanese EUA Development Bill" submitted to the Diet by members of the House of Representatives Katsuhito Nakajima of the Constitutional Democratic Party, who are also doctors. However, it is still a shelf due to the recess of the Diet.
Mr. Nakajima, the first proposer, says, "If this bill is passed, everything will be solved." Ivermectin, a scabies treatment, will be available for corona treatment, paving way for the use of generic preparations, and health hazards such as side effects can be remedyed. I think doctors will actively prescribe this.
The vaccination rate for the Japanese people as a whole has not reached about 50% for the first time and 40% for the second time. The biggest concern of President Ozaki of the Tokyo Medical Association, which has the largest regional population in Japan, is to deal with the tightness of medical facilities that accept severe patients, and the sudden change of home care workers. Chairman Ozaki's words had a sense of crisis that we had no choice but to use Ivermectin urgently.
Ivermectin discovered in Japan has the potential to become a "savior" of the coronavirus pandemic. Looking at the clinical trial reports around the world so far, it's impossible that it doesn't work at all. Many countries, including India, have a track record of urgently administering ivermectin to reduce the spread of infection. In an emergency, there is no reason to hesitate to use it for coronavirus infection. I'm sure the utilization of Ivermectin is by no means a "bet".
Sent from my iPad using Tapatalk
Feels like a game of whack a mole
I've gotta ask catscollector ,WTF is it about that post that you 'loved'?Not on the official Ministry of Health prescribed medication for covid but used by GP’s and pushed by the Chairman of the Tokyo Medical Association even up until August. How widespread use on a local level is hard to quantify. This article gives the best breakdown of the situation
「今こそイベルメクチンを使え」東京都医師会の尾崎治夫会長が語ったその効能
【読売新聞】ＰＯＩＮＴ ■イベルメクチンが新型コロナの予防にも治療にも効果があるという論文が相次いで発表されているが、すでに「使用国」とされている日本では使用が進んでいない。 ■感染爆発が進む今こそ使用すべきだが、使おうにもイベルメ
Translated
"Now is the time to use ivermectin," Haruo Ozaki, chairman of the Tokyo Medical Association, talked about its efficacy.
2021/08/19 10:55 AM
Contributions Research and Research
Scrap this article
POINT
■Thesis that Ivermectin is effective in preventing and treating COVID-19 has been published one after another, but it has not been used in Japan, which is already considered to be a "country of use".
■It should be used now that the infection explosion is progressing, but there are issues such as not having ibermectin to use it, and not being subject to the government's side effects damage relief system.
■If the Japanese version of the EUA is developed quickly and the doctors on the field can use it, it can be administered to patients staying at home and recuperating. The government should actively work on promoting use.
Delta strains originating in India are raging during the Tokyo Olympics, and the number of infected people continues to spread. Why doesn't Japan use ivermectin, which has been reported in clinical trials in other countries with few reports of side effects? On August 5, we had an emergency interview with President Ozaki of the Tokyo Medical Association, who has been advocating effective use of ivermectin from an early age.
Interviewer and composition Certified NPO, Chairman of the 21st Century Concept Study Group
Scientific journalist Rensei Baba
The peak of the spread of infection that can not be seen yet
――This explosive spread of infection, which is said to be the fifth wave, seems to be still rising to the right. The number of people waiting at home and recuperating is increasing rapidly. How does the Tokyo Medical Association respond?
"When the number of people who wait at home and recuperate increased rapidly in the third wave of January, this was no good, and the Tokyo Metropolitan Medical Association worked together to build a system with the goal of 24-hour support, and up to 37 out of the 47 District Medical Associations. It became. However, the current situation where more than 1000 home recuperators accumulate every day is beyond the limit. Doctors in the clinic can't handle general medical care, vaccination, medical checkup, house call, etc. The public health center is adjusting the hospitalization now. There is also a hospitalization adjustment center in Tokyo, but it has not been established to establish a system that can quickly accept and treat sudden changes of coronavirus patients."
Many clinical trial results are "effective for prevention and treatment".
――If you read the paper on clinical trials of Ivermectin that have been published around the world so far, there are many examples that are effective for prevention and treatment.
"I understand that there are many thesis that Ivermectin is effective in preventing and treating corona, mainly in Latin America and Asia. I'm forced to deal with patients who develop one after another, but there are no effective treatments. The vaccine won't be in time. When such an imminent situation occurs, there is a paper that Ivermectin is effective against corona, so it is a natural response for a clinician to try using this. That's why many doctor-led clinical trial papers came out because of that."
Ivermectin
Ivermectin
――Normally, pharmaceutical companies do large clinical trials to see the effect, but Ivermectin is a special medicine for tropical diseases such as oncocercaemia (river blindness) and lymphatic filariasis, including the World Health Organization (WHO) and other countries around the world It's a drug approved more than 20 years ago. If it's also effective for COVID-19, it's out of adaptation, but it's unavoidable that we decided to use it during the pandemic.
That's right. The medical field of the pandemic is a battlefield. It's the same as Field Hospital. Patients are brought in and their condition gets worse one after another and they die. At that time, there were almost no side effects, and many papers came out that it would work on corona virus, so I understand the doctor's feelings of clinging to this and administering it well."
"Just the other day, a research group of All India Institute of Medical Sciences/AIIMS, which has decided on guidelines for treating coronavirus infections in India, has been I'm publishing a paper that examines the preventive effect of Kuchin. According to it, about 3900 medical workers (staff and students) weighed 0 per kilogram of Ivermectin. As a result of clinical trials divided into three groups of 3 milligrams administered twice every three days, the group that was administered only once, and the group that did not administered it, the number of people who received Ivermectin twice decreased by 83% in COVID-19 infection. It's. The paper was published by the world's first-class research group, so it's very reliable."
――In Japan, we have admitted that Ivermectin will be used for COVID-19 treatment from the "Guide to COVID-19 Treatment Guide for COVID-19" noted on May 18, 2020. Even in the world, Japan is divided into countries where Ivermectin is used.
"In Japan, Ivermectin has been approved as an indication under the product name "Stromectol" for scabies for skin diseases, etc. for a long time, and the revised guide has provided a notice to approve the treatment of COVID-19 as "out of adaptation". I am. Out of adaptation means that it can be used at the discretion of doctors and patients. By the time the notice was issued, 36 clinical trials were conducted in 27 countries in the world, and it was reported that ivermectin was effective in preventing and treating. That's why the Ministry of Health, Labour and Welfare also admitted it out of the scope. If it doesn't work, if it's out, we won't be not going to notice."
The government is positive about using the Diet, but...
――In the Diet, the government is also responding to the use of yvermectin.
"At the budget committee of the House of Representatives on February 17, Katsuhito Nakajima, a member of the Constitutional Democratic Party, proposed about ivermectin, "We should do our best back up the trial so that we can approve it as an early treatment for coronavirus as possible as the country." I did. Minister of Health, Labour and Welfare Tamura said, "It can still be used for non-adaptive use. There is also a way to use it to take it at a medical institution and wait at home. Prime Minister Suga replied, "I think it's a very important medicine for Japan, so I'll do my best," and showed his active efforts. But in reality, we haven't been able to do it."
――Why can't you do it?
"We also investigated what kind of supply system Merck in the United States, which supplies approved drugs in Japan and beyond that. Probably because Merck is developing a therapeutic drug, Ivermectin is not effective in treating and preventing COVID-19, and intends not to use it other than skin diseases such as scabies. In other words, even if you use it for COVID-19, if Merck doesn't actually come out, it won't lead to domestic Ivermectin supply. Even if the doctor writes a prescription for Ivermectin, the pharmacy doesn't have any drugs. This will virtually not be usable."
"But (Merk) says that Ivermectin doesn't work, so there's no need to limit the supply. If it doesn't work, there's no demand. I believe it will work, so it looks like it's blocking the supply."
The reason why generics don't spread is
――Ivermectin's generic chemicals are also manufactured in large quantities in China, India, etc. If Merck doesn't issue it, there should be a way to import and supply it.
That's right. If the "Special Measures Bill for Designation and Use of Specific Drugs for therapeutic Use of New Influenza" (Japanese version EUA* Development Bill) submitted to the House of Representatives led by Mr. Nakajima, who is also a doctor, will be able to use generic preparations. I will do it. But at the moment, the government is not moving at all."
"Another problem is that ivermectin has already been used in many countries in the world, and usage, dosage, safety and effectiveness have been confirmed, but that has not yet been done in the clinical trial stage in Japan. Therefore, Ivermectin is not subject to the damage relief system for pharmaceutical side effects. This makes it difficult for doctors to use. However, even in such anxiety and disadvantageous circumstances, some doctors who are convinced of the effect of ivermectin have prescribed ivermectin at their own risk. I hope the Japanese EUA Development Act will be enacted soon."
*EUA (Emergency Use Authorization) The U.S. Food and Drug Administration (FDA) system that allows the use of unauthorized drugs in case of emergency and expands the application of approved drugs. The merit of using , which is a life-threatening disease that can be recognized as a certain efficacy in the treatment of the disease, exceeds the potential risk of the product and other suitable alternatives to diagnose, prevent or treat diseases. If it is judged that it meets the condition of "い――", it can be used.
――Since it has been admitted that it is not adapted, Japan is divided into "the country of use of Ivermectin" in the world, but it is a system that can not be used in reality.
That's right. In short, the government has not built a system that can supply Ivermectin, so it is not a promotion system. If the Japanese version of the EUA is developed quickly and the doctors in the field can use it, as Minister of Health, Labour and Welfare Tamura responded in the Diet, it can be realistically administered to patients staying at home and recuperating, but the current system can virtually do anything. It is often said that it is "for the safety of the people", but if you don't lose your cautious attitude even in such an emergency, you can only understand that you are sacrificing the safety of the people."
Academic sites and researchers who don't touch themselves
――Is there any other problem in Japan?
"Ivermectin is a drug discovered by Dr. Satoshi Omura and won the Nobel Prize. Whether it really works on Corona or not, Japan should have the ability to work on it ahead of the world. The WHO and the National Institutes of Health (NIH) in the United States continue to take the view that the effect on corona virus is undecided, but since Ivermectin is used all over the world during the pandemic, scientific evidence (evidence) If the clinical trials obtained are conducted by the government and show objective and convincing conclusions, it will lead to an increase in Japanese research standards."
"A group of American clinicians (FLCCC) published the results that ivermectin is effective against corona in South America and Asia, and doctor groups such as Ivermectin Recommendation Organization (BIRD) in the UK have published many papers. We are convinced that it is "effective" from the meta analysis that comprehensively analyzes, and we recommend ivermectin to medical fields around the world. I also told the Japanese Olympic Committee that Ivermectin should be used effectively when holding the Tokyo Olympics, but the government didn't respond to anything."
"There are also problems with academic researchers and university teachers. Many people don't do anything by themselves, and they have their own view that "Ivermectin is undecided whether it will work for coronavirus" issued by international organizations such as WHO and large health organizations in Europe and the United States. Don't do it proactively, it's only moving with people's opinions. Why don't you feel like checking on your own whether Ivermectin works or not? It's sad that there are critics, researchers, and scholars who are always criticizing without doing it. I want Japanese academia to contribute more actively."
The Tokyo Medical Association "I want to work on using it."
――In Japan, clinical trials centered on Kowa, a major pharmaceutical company, are finally scheduled to be conducted. How do you deal with it?
In January 2021, after the exchange of opinions for the development of the vaccination system, Gover nor Yuriko Koike and Chairman Ozaki of Tokyo (left) responded to interviews by the press.
In January 2021, after the exchange of opinions for the development of the vaccination system, Governor Yuriko Koike and Chairman Ozaki of Tokyo (left) responded to interviews by the press.
"The Tokyo Metropolitan Government and the Medical Association are planning to actively support and cooperate with this clinical trial. I decided to actively search and provide medical institutions to cooperate with. There's nothing we can do in a country that relies on vaccines and therapeutic drugs developed by foreign countries. It is our thing to properly put out the data of Ivermectin ourselves and aim to contribute to the severity and decrease in death as a Japanese."
――What should the Japanese health system learn from the experience of the coronavirus pandemic?
"Unduring the Japan's universal insurance system, it has been clear that the response in the event of a pandemic like this time is severe. Private medical facilities are managed by increasing the occupancy rate to the fullest and increasing efficiency. Under such situations, it is extremely difficult to be told to deal with it because the number of infected people has increased rapidly like this time.
"For example of countermeasures, we build hospitals with about 1,000 vacant beds at public medical institutions and hospitals, and usually operate them as training and training institutions for research facilities, doctors, nurses, and laboratory technicians, and in the event of a pandemic, doctors There is a way to use it as a medical institution. We will hone our skills, train human resources, and make it a system that allows us to introduce human resources that we have nurtured in the event of a pandemic. I think there are also challenges to materialize the operation method, but I think we should consider and study in the future."
after the interview
There is also a backlash against WHO who is cautious about use.
Under the circumstances where Delta strains (Indian mutants) are about to replace almost all of the infected people in Japan, the number of new cases of COVID-19 is hitting a record high every day.
The number of home recuperators in Tokyo exceeds 20,000 and more than 70,000 nationwide. Katsuhito Nakajima, a member of the House of Representatives, who is also a doctor, said, "Antibody cocktail therapy is effective, but there are challenges in the amount of security and system development. In order to prevent the severity of coronavirus patients, it is necessary to expand the choice of early treatment." I felt that one of the options was the administration of Ivermectin strongly moving Chairman Ozaki.
Tedros WHO Executive Director
Tedros WHO Executive Director
The evaluation of ivermectin for corona treatment and prevention has not hardened yet. Major health organizations in the world, such as WHO and NIH, maintain the view that "there are no clinical trial results that show evidence enough to convince scientists around the world". However, it is also true that there are many groups of doctors in the United States and the United Kingdom who oppose that "these claims are unfounded".
While some people are seriously ill and die, doctors are working hard day and night in medical settings around the world. India's medical field during the rapid spread of infection was just a battlefield. In medical fields where there are not enough therapeutic drugs or therapeutic equipment, Ivermectin was administered relying on many papers that it was effective against COVID-19, and many cases have greatly affected.
The Indian Bar Association made a document that violently criticized the WHO's not recommending Ivermectin for the use of treatment, saying that it is equivalent to a murder charge to letting patients die, and send it to Secretary-General Tedros and Chief Scientist, and sends the document to the world. It's publishing it to the world.
The medical groups that have the effect of ivermectin are FLCC in the United States and BIRD in the UK. The FLCCC summarizes the results of 63 clinical trials meta-analysis (as of August 15) conducted by 613 scientists (doctors and researchers) around the world for 26,398, and judged as follows.
▽86% of the preventive effect in 14 preventive tests
▽73% improvement effect in 27 initial symptom treatment tests
▽40% improvement effect in 22 severe treatment tests
▽Degraded mortality rate by 61% in 25 clinical trials
About half of the 31 meta-analyzed cases are considered the global clinical trial standards, and randomized controlled trials (RCTs) that emphasize evidence, and 60% of them have improved here. Chairman Ozaki believes this and shows that there may be clinicians who believe in this and try to use ivelmectin for treatment.
The claim to deny ivermectin is also persistent.
On the other hand, it is true that there are persistent voices of doubts and opposition to using ivermectin for the treatment and prevention of corona. I read three papers that have no ibermectin effect, and two of them were pointed out by researchers that there was a mistake in the method of clinical trials. Isn't there any other paper that doesn't work?
Certainly, there were cases where the papers of the Egyptian doctor group, which was "effective", were pointed out that the data was suspected of fabricated and withdrawn. However, as mentioned above, the fact that Ivermectin is overwhelmingly more effective for COVID-19 is unwavering. Ivermectin has almost no side effects, generics are widespread and the price is cheap. The idea of using it is not reckless. Isn't denying the use possible to destroy the countermeasures against the pandemic?
Expect the Japanese EUA bill to be passed.
The Minister of Health, Labour and Welfare Tamura said in the Diet that it can still be used for non-applicable use. There is also a way to take (Ivermectin) at a medical institution and wait at home," he replied. If this is easy to do, there is no need for the Tokyo Medical Association to insist that "Ivermectin should be used".
Chairman Ozaki said, "In non-adaptive use, even if there is a health injury due to side effects, it will not be subject to the relief system, and first of all, there is nothing to prescribe." Unless generic preparations can be used, Ivermectin will continue to be a "medication that can't be used forever" realistically.
Beyond that wall is the enactment of the "Japanese EUA Development Bill" submitted to the Diet by members of the House of Representatives Katsuhito Nakajima of the Constitutional Democratic Party, who are also doctors. However, it is still a shelf due to the recess of the Diet.
Mr. Nakajima, the first proposer, says, "If this bill is passed, everything will be solved." Ivermectin, a scabies treatment, will be available for corona treatment, paving way for the use of generic preparations, and health hazards such as side effects can be remedyed. I think doctors will actively prescribe this.
The vaccination rate for the Japanese people as a whole has not reached about 50% for the first time and 40% for the second time. The biggest concern of President Ozaki of the Tokyo Medical Association, which has the largest regional population in Japan, is to deal with the tightness of medical facilities that accept severe patients, and the sudden change of home care workers. Chairman Ozaki's words had a sense of crisis that we had no choice but to use Ivermectin urgently.
Ivermectin discovered in Japan has the potential to become a "savior" of the coronavirus pandemic. Looking at the clinical trial reports around the world so far, it's impossible that it doesn't work at all. Many countries, including India, have a track record of urgently administering ivermectin to reduce the spread of infection. In an emergency, there is no reason to hesitate to use it for coronavirus infection. I'm sure the utilization of Ivermectin is by no means a "bet".
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I presume you mean 88% of people in icu havent had a jab?
not sure what victoria youre living in but we arent locked down here
