I agree with Iddy Biddy that anything before about 1997 was so compromised in various ways, that we're not comparing apples with apples. I have excluded the rookie draft (where the obvious stars are Cox, Kirk, Rutten) because I don't view that as being within the scope of the question. So, with that in mind:
Most inspired: Adam Goodes, pick 43, 1997. Many champion players have come from low picks; but here with a mediocre pick Sydney changed the draft game, putting the focus on body type.
Least inspired: Dylan Smith, pick 6, 2000. There are many top 10 failures. What's notable about Smith? The Roos' recruiters were in sterling form in 2000*. Except for their highest pick.
(* Motlop, Harris, Petrie, Rocca, Pratt, Jones.)
Most inspired: Adam Goodes, pick 43, 1997. Many champion players have come from low picks; but here with a mediocre pick Sydney changed the draft game, putting the focus on body type.
Least inspired: Dylan Smith, pick 6, 2000. There are many top 10 failures. What's notable about Smith? The Roos' recruiters were in sterling form in 2000*. Except for their highest pick.
(* Motlop, Harris, Petrie, Rocca, Pratt, Jones.)